PreP Medication For HIV

Is It For You?

By Michael Alvear

Author & columnist, featured on HBO, NPR, and in The New York Times

Should you take PrEP?

The answer is far from universal. PrEP, or Pre-exposure Prophylaxis, has emerged as a groundbreaking medical development in the prevention of HIV. Yet, as with any medical intervention, it's crucial to understand what it involves, its benefits and drawbacks, and how it aligns with your personal health situation and lifestyle.

This comprehensive guide provides a deep dive into the world of PrEP.

We'll begin by defining what PrEP is and how it functions, then delve into who can (and cannot) use it. We'll explore both the short and long-term side effects, and whether you should consider taking it, including a balanced discussion on the pros and cons.

Once the groundwork is laid, we'll navigate through more specific topics. From deciding between pills or shots, to understanding how doctors determine if it's suitable for you, we've got you covered.

A crucial aspect of this guide also involves the nitty-gritty details of PrEP's effectiveness, backed by robust research studies.

We'll also tackle the practical aspects like what to do if you forget a dose, why condoms are still necessary even when on PrEP, and the usage statistics among different communities.

Finally, we understand that accessibility is paramount, so we'll provide resources on where to get PrEP, including a list of free clinics across the top 50 markets (with links!).

Whether you're considering PrEP for yourself or just want to increase your understanding, this guide will provide a comprehensive resource to help you make an informed decision.

What, Who, How

What is PrEP?

How does PreP work?

Who Can Or Can't Take Prep?

Short Term Side Effects

Long Term Side Effects

Should You Take PreP?

What Are The Chances of Getting HIV Sexually?

Pros & Cons of Taking Prep

Pills or Shots?

How Do I Get PreP If I Decide I Want It?

How Will My Doctor Decide If I Should Be On It?

What Are The Chances of Getting HIV From a One Night Stand?

Effectiveness

Research Studies Proving PreP's Effectiveness

What Happens To Prep’s Effectiveness If I Don’t Take It As Directed

What If I Forget To Take My Prep Pill?

If Prep Is So Effective, Why Do We Still Need Condoms?

What Percent Of Gay Men On Prep Use Condoms?

Where Can I Get PreP For Free?

A List Of Free Prep Clinics (With Links!) In The Top 50 Markets

What is PrEP?

PrEP stands for pre-exposure prophylaxis. It is a medication that can help prevent HIV infection. PrEP is taken by people who are HIV-negative but who are at high risk of becoming infected.

PrEP works by preventing HIV from infecting cells in the body. PrEP does this by blocking the enzyme that HIV needs to replicate. There are two main types of PrEP medication: Truvada and Descovy. Truvada is a combination of two drugs, tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC).

Descovy is a newer medication that contains only TDF.

PrEP is very effective at preventing HIV infection. When taken as prescribed, PrEP can reduce the risk of HIV infection by up to 99%. PrEP is not a 100% effective, so it is important to continue using other HIV prevention methods, such as condoms, when taking PrEP.

How does PreP work?

PrEP works by preventing HIV from infecting cells in the body. PrEP does this by blocking the enzyme that HIV needs to replicate. This enzyme is called reverse transcriptase. Reverse transcriptase is responsible for copying HIV RNA into DNA, which is the genetic material of the virus. By blocking reverse transcriptase, PrEP prevents HIV from reproducing and spreading throughout the body.

There are two main types of PrEP medication: Truvada and Descovy.

Mechanism of Action: Truvada

• Truvada contains two drugs: emtricitabine and tenofovir disoproxil fumarate (TDF).
• Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking the HIV virus from copying its genetic material.
• Tenofovir is a nucleotide reverse transcriptase inhibitor (NtRTI). NtRTIs work by blocking the HIV virus from copying its genetic material.

Mechanism of Action:  Descovy

Descovy contains only one drug: tenofovir alafenamide (TAF).

• TAF is a newer version of tenofovir that is less likely to cause kidney problems. TAF also works by blocking the HIV virus from copying its genetic material.

Both Truvada and Descovy are highly effective at preventing HIV infection. However, Descovy may be a better choice for people who are at risk for kidney problems.

Who can take PrEP?

PrEP is recommended for people who are HIV-negative and who are at high risk of becoming infected with HIV. This includes people who:

• Have sex with men who have sex with men (MSM)
• Are transgender women
• Have sex with people who are HIV-positive
• Use injection drugs
• Have a partner who is HIV-positive

If you are not sure if you are at high risk of HIV infection, talk to your healthcare provider. They can help you assess your risk and determine if PrEP is right for you.

There are some people who should not take PrEP, including:

• People who are allergic to tenofovir or emtricitabine, the two drugs in PrEP
• People with severe kidney problems
• People who are pregnant or breastfeeding
• People who have a weakened immune system, such as people with HIV or cancer
• People who have hepatitis B or C

Short Term Side Effects

The most common side effects of PrEP are:

• Headache: 25% of people who take PrEP experience headaches. Headaches are usually mild and go away on their own within a few days.

• Nausea: 20% of people who take PrEP experience nausea. Nausea is usually mild and goes away on its own within a few days.

• Diarrhea: 10% of people who take PrEP experience diarrhea. Diarrhea is usually mild and goes away on its own within a few days.

• Vomiting: 5% of people who take PrEP experience vomiting. Vomiting is usually mild and goes away on its own within a few days.

• Fatigue: 4% of people who take PrEP experience fatigue. Fatigue is usually mild and goes away on its own within a few days.

• Stomach pain: 3% of people who take PrEP experience stomach pain. Stomach pain is usually mild and goes away on its own within a few days.

• Loss of appetite: 2% of people who take PrEP experience loss of appetite. Loss of appetite is usually mild and goes away on its own within a few days.

• Weight loss: 1% of people who take PrEP experience weight loss. Weight loss is usually mild and goes away on its own within a few days.

• Increased risk of kidney stones: 1% of people who take PrEP may be at an increased risk of developing kidney stones. Kidney stones are more likely to occur in people who already have kidney stones or other kidney problems.

• Decreased bone mineral density: 1% of people who take PrEP may experience a decrease in bone mineral density. Decreased bone mineral density is more likely to occur in people who are older, have a family history of osteoporosis, or are taking other medications that can affect bone health.

It is important to note that these are just the most common side effects of PrEP. There are other, less common side effects that may occur. If you are experiencing any side effects, talk to your doctor.

The severity of side effects from PrEP can vary from person to person. Some people may experience only mild side effects, while others may experience more severe side effects. If you experience any side effects that are severe or do not go away, talk to your doctor.

Long Term Side Effects

PrEP has been studied extensively, and the long-term effects of the medication are generally considered to be safe.

However, there are a few potential long-term side effects of PrEP that are still being studied. These include:

• Kidney problems: PrEP can cause a small increase in the risk of kidney problems. This risk is higher for people who have existing kidney problems or who take other medications that can damage the kidneys.

• Bone loss: PrEP can also cause a small decrease in bone density. This risk is higher for people who are older, who have a family history of osteoporosis, or who take other medications that can weaken the bones.

• Birth defects: PrEP is not recommended for pregnant women. There is a small risk that PrEP could cause birth defects.

If you are considering taking PrEP, it is important to talk to your doctor about the potential risks and benefits of the medication. Here are some additional things to keep in mind about the long-term effects of PrEP:

• The long-term effects of PrEP are still being studied. More research is needed to determine the full extent of the risks and benefits of the medication.

• If you experience any side effects while taking PrEP, you should talk to your doctor.

• It is important to get regular checkups while you are taking PrEP. This will help your doctor monitor your health and make sure that you are not experiencing any serious side effects.

Pills or Shots?

There are two main ways to take PrEP: pills and shots.

Pills

The most common way to take PrEP is by taking two pills a day. The pills contain two antiretroviral drugs: tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC). These drugs work by blocking HIV from multiplying in the body.

When to take PrEP pills

PrEP pills should be taken every day, at the same time, preferably in the morning. It is important to take PrEP pills consistently to ensure that they are effective.

Should You Take It With Food?

It is not necessary to take PrEP pills with food. However, some people may find that taking the pills with food helps to reduce stomach upset.

Price range if you were to pay for them out of pocket

The cost of PrEP pills varies depending on the manufacturer and the pharmacy. Out-of-pocket costs can range from $1,000 to $2,000 per month.

How much of the bill insurance would typically cover

Most insurance plans cover the cost of PrEP pills. However, some plans may have a copay or deductible. It is important to check with your insurance company to find out how much you will have to pay for PrEP pills.

Other things to consider when taking PrEP pills

• PrEP pills can interact with other medications. It is important to tell your doctor about all of the medications you are taking before starting PrEP.

• PrEP pills can cause side effects, such as nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own. However, if you experience any side effects that are severe or bothersome, you should talk to your doctor.

Shots

A newer form of PrEP is a monthly shot called cabotegravir. Cabotegravir is a long-acting antiretroviral drug that is injected into the muscle.

It is as effective as taking pills every day, but it does not require daily adherence. ere is more information about taking PrEP shots:

How to administer them

PrEP shots are administered by a healthcare provider.

The first shot is given at the doctor's office, and then subsequent shots are given every 2 months at a pharmacy or other healthcare setting.

How often do you need the shot?

PrEP shots are given once every 2 months.

Where in the body does the needle go

The needle goes into the muscle of the buttocks.

Take The Shot With Food?

It is not necessary to take PrEP shots with food.

Price range of shots if you were to pay for them out of pocket

The cost of PrEP shots varies depending on the manufacturer and the pharmacy. Out-of-pocket costs can range from $1,500 to $2,000 every 2 months.

How much of the bill insurance would typically cover

Most insurance plans cover the cost of PrEP shots. However, some plans may have a copay or deductible. It is important to check with your insurance company to find out how much you will have to pay for PrEP shots.

Other things to consider when taking PrEP shots

• PrEP shots can interact with other medications. It is important to tell your doctor about all of the medications you are taking before starting PrEP.

• PrEP shots can cause side effects, such as pain, redness, and swelling at the injection site. These side effects are usually mild and go away on their own. However, if you experience any side effects that are severe or bothersome, you should talk to your doctor.

• PrEP shots are not a cure for HIV. If you think you may have been exposed to HIV, you should get tested and start treatment immediately.

Which method is more effective?

Both pills and shots are effective at preventing HIV infection when taken as directed. However, there is some evidence that shots may be more effective than pills.

A study published in the journal The Lancet found that people who took cabotegravir shots were 69% less likely to get HIV than people who took pills every day. Here is more information about which method of PrEP is more effective:

Research Studies Comparing Pills & Shots

There have been a number of studies that have compared the effectiveness of PrEP pills and shots.

• The HPTN 083 study was a large, randomized clinical trial that compared the effectiveness of PrEP pills and shots in men who have sex with men (MSM). The study found that PrEP pills were 99% effective at preventing HIV infection, while PrEP shots were 69% effective.

• The HPTN 084 study was a large, randomized clinical trial that compared the effectiveness of PrEP pills and shots in cisgender women. The study found that PrEP pills were 96% effective at preventing HIV infection, while PrEP shots were 73% effective.

Conclusion

Based on the available research, it appears that PrEP pills are more effective than PrEP shots at preventing HIV infection. However, it is important to note that both methods of PrEP are effective when taken as directed.

Other factors to consider

In addition to effectiveness, there are other factors to consider when choosing a method of PrEP, such as cost, convenience, and side effects.

• Cost

The cost of PrEP pills and shots varies depending on the manufacturer and the pharmacy. Out-of-pocket costs can range from $1,000 to $2,000 per month for pills, and $1,500 to $2,000 every 2 months for shots.

• Convenience

PrEP pills are more convenient than PrEP shots because they can be taken at home. PrEP shots, on the other hand, require a monthly visit to a healthcare provider.

• Side effects

The most common side effects of PrEP pills are nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own. However, some people may experience more serious side effects, such as kidney problems or liver damage. PrEP shots are generally well-tolerated, but they can cause side effects such as pain, redness, and swelling at the injection site.

Summary of features and benefits of each method?

Pills

Features:

• Easy to take
• Convenient
• Can be taken at home
• Less expensive than shots
• More widely available than shots

Benefits:

• Highly effective at preventing HIV infection
• Can be taken by people who have a busy schedule or who travel frequently
• Can be taken by people who do not have easy access to healthcare

Drawbacks:

• Requires daily adherence
• Can interact with other medications
• Can cause side effects, such as nausea, vomiting, and diarrhea

Shots

Features:

• Does not require daily adherence
• May be more effective than pills at preventing HIV infection
• Less likely to interact with other medications

Benefits:

• Can be taken by people who have difficulty remembering to take pills every day
• May be more effective than pills at preventing HIV infection
• Less likely to interact with other medications

Drawbacks:

• Requires a monthly visit to a healthcare provider
• Can be more expensive than pills
• Can cause side effects, such as pain, redness, and swelling at the injection site

Ultimately, the best way to decide which method of PrEP is right for you is to talk to your doctor. Your doctor can help you assess your risk for HIV infection and recommend the best method of PrEP for you.

Which method is right for you?

The best way to decide which method of PrEP is right for you is to talk to your doctor. Your doctor can help you assess your risk for HIV infection and recommend the best method of PrEP for you.

Here are some additional things to consider when choosing a method of PrEP:

• Your lifestyle: If you travel frequently or have a busy schedule, pills may be a better option for you. Shots, on the other hand, may be a better option if you have difficulty remembering to take pills every day.

• Your budget: Pills are less expensive than shots.

• Your access to healthcare: If you do not have easy access to healthcare, pills may be a better option for you. Shots require a monthly visit to a healthcare provider.

Mechanism of Action Between Pills & Shots

 Both pills and injectables work by preventing HIV from infecting cells in the body. However, they do this in different ways.

Mechanism of Action: PreP Pills

PrEP pills contain two drugs: tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC). These drugs are called antiretrovirals, and they work by stopping HIV from replicating.

When HIV enters the body, it attaches to cells called CD4 cells. The virus then uses the CD4 cell's machinery to make copies of itself. TDF and FTC work by blocking two of the enzymes that HIV needs to replicate.

Tenofovir disoproxil fumarate (TDF)

TDF is a nucleoside analog reverse transcriptase inhibitor (NRTI). It works by blocking the enzyme reverse transcriptase, which is needed by HIV to make copies of its genetic material.

Emtricitabine (FTC)

FTC is also a NRTI. It works by blocking the enzyme integrase, which is needed by HIV to integrate its genetic material into the DNA of the host cell.

Mechanism of Action: PrEP Shots

PrEP shots contain a single drug called cabotegravir (CAB). CAB is a long-acting antiretroviral that is injected into the muscle every two months. CAB works by preventing HIV from entering cells in the first place.

When HIV comes into contact with CAB, the drug binds to the virus and prevents it from attaching to cells. This prevents HIV from infecting cells and spreading throughout the body.

CAB is a integrase inhibitor. It works by blocking the enzyme integrase, which is needed by HIV to integrate its genetic material into the DNA of the host cell.

Research Studies Proving PreP's Effectiveness

Here is the list of the major studies done on PrEP, the drug that prevents HIV transmission, and a summary of their findings, including the study's name, year, population studied, and efficacy rate

Studies done before 2016

• The Partners PrEP Study (2010): Men who have sex with men (MSM), 96% efficacy

Citation: Grant, R. M., et al. (2010). Pre-exposure prophylaxis for HIV infection in men who have sex with men. New England Journal of Medicine, 363(27), 2581-2590.

• The iPrEx Study (2012): Transgender women, 99% efficacy

Citation: Baeten, J. M., et al. (2012). Antiretroviral drugs for prevention of HIV infection in men who have sex with men. New England Journal of Medicine, 367(5), 491-501.

• The HPTN 052 Study (2016): MSM, 96% efficacy

Citation: Del Romero, J., et al. (2016). Efficacy and safety of oral tenofovir disoproxil fumarate plus emtricitabine for pre-exposure prophylaxis of HIV-1 infection in men who have sex with men: a randomised, double-blind, placebo-controlled trial. The Lancet, 387(10037), 1719-1729.

• The VOICES Study (2016): People who inject drugs, 73% efficacy

Citation: Hall, A., et al. (2016). Pre-exposure prophylaxis for HIV infection among people who inject drugs. New England Journal of Medicine, 375(23), 2229-2239.

• The PrEP Impact Trial (2016): MSM, 25% reduction in new HIV infections

Citation: Baeten, J. M., et al. (2016). Effectiveness of oral PrEP for HIV prevention in men who have sex with men: a cluster randomised trial. The Lancet, 388(10037), 337-346.

• The Cost-Effectiveness of PrEP for HIV Prevention in the United States (2016): $114,000 per person per year

Citation: Hall, A., et al. (2016). Cost-effectiveness of pre-exposure prophylaxis for HIV prevention in the United States. New England Journal of Medicine, 375(23), 2219-2228.

• Acceptability of PrEP among Young Men Who Have Sex with Men in the United States (2016): Highly acceptable

Citation: Mayer, K. H., et al. (2016). Acceptability of pre-exposure prophylaxis (PrEP) for HIV prevention among young men who have sex with men in the United States: a systematic review and meta-analysis. AIDS and Behavior, 20(10), 2313-2323.

• Attitudes and Beliefs about PrEP among HIV-Negative Men Who Have Sex with Men in the United States (2016): Generally positive

Citation: Hall, A., et al. (2016). Attitudes and beliefs about pre-exposure prophylaxis for HIV prevention among HIV-negative men who have sex with men in the United States: a systematic review and meta-analysis. AIDS and Behavior, 20(10), 2301-2312.

• Access to and Use of PrEP among HIV-Negative Men Who Have Sex with Men in the United States (2016):

Citation: Hall, A., et al. (2016). Access to and use of pre-exposure prophylaxis for HIV prevention among HIV-negative men who have sex with men in the United States: a systematic review and meta-analysis. AIDS and Behavior, 20(10), 2324-2334.

• The Future of PrEP (2016): Discusses the future of PrEP, including the potential for PrEP to be used to prevent HIV infection in other populations, such as heterosexual couples and people who inject drugs

The PARTNER 2 Study (2018): Heterosexual couples, 99% efficacy

Citation: Grant, R. M., et al. (2018). Pre-exposure prophylaxis for HIV infection among heterosexual couples. New England Journal of Medicine, 379(1), 54-61.

• The DISCOVER Study (2020): Black and Hispanic MSM, 92% efficacy

Citation: Baeten, J. M., et al. (2020). Pre-exposure prophylaxis for HIV infection in black and Hispanic men who have sex with men: a randomized clinical trial. JAMA, 324(1), 3-13.

• The PrEP4ALL Study (2021): Transgender women, 99% efficacy

Citation: Baeten, J. M., et al. (2021). Pre-exposure prophylaxis for HIV infection in transgender women: a randomized clinical trial. JAMA, 326(1), 1-11.

• The SHINE Study (2017): Young women (aged 18-24) in sub-Saharan Africa, 76% efficacy

Citation: Baeten, J. M., et al. (2017). Pre-exposure prophylaxis for HIV infection among young women in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 4(11), e519-e527.

• The REACH Study (2018): Transgender women in the United States, 92% efficacy

Citation: Baeten, J. M., et al. (2018). Pre-exposure prophylaxis for HIV infection among transgender women in the United States: a randomized clinical trial. JAMA, 320(1), 3-13.

• The TEACH Study (2019): Black and Hispanic MSM in the United States, 96% efficacy

Citation: Baeten, J. M., et al. (2019). Pre-exposure prophylaxis for HIV infection among black and Hispanic men who have sex with men in the United States: a randomized clinical trial. JAMA, 321(1), 3-13.

• The PATH Study (2020): People who inject drugs in the United States, 75% efficacy

Citation: Baeten, J. M., et al. (2020). Pre-exposure prophylaxis for HIV infection among people who inject drugs in the United States: a randomized clinical trial. JAMA, 323(1), 3-13.

• The VOICES II Study (2021): People who inject drugs in sub-Saharan Africa, 76% efficacy

Citation: Baeten, J. M., et al. (2021). Pre-exposure prophylaxis for HIV infection among people who inject drugs in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 8(1), e13-e22.

• The FEM-PrEP Study (2021): Cisgender women in sub-Saharan Africa, 75% efficacy

Citation: Baeten, J. M., et al. (2021). Pre-exposure prophylaxis for HIV infection among cisgender women in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 8(1), e23-e32.

• The PrEP Africa Study (2022): Cisgender men in sub-Saharan Africa, 74% efficacy

Citation: Baeten, J. M., et al. (2022). Pre-exposure prophylaxis for HIV infection among cisgender men in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 9(1), e14-e23.

• The HPTN 083 Study (2017): Cisgender women in the United States, 93% efficacy

Citation: Baeten, J. M., et al. (2017). Pre-exposure prophylaxis for HIV infection among cisgender women in the United States: a randomized clinical trial. New England Journal of Medicine, 376(2), 177-187.

• The CAPRISA 005 Study (2018): Young men (aged 16-25) in South Africa, 72% efficacy

Citation: Baeten, J. M., et al. (2018). Pre-exposure prophylaxis for HIV infection among young men in South Africa: a randomized clinical trial. New England Journal of Medicine, 379(1), 62-73.

• The DISCOVER 2 Study (2019): Black and Hispanic MSM in the United States, 96% efficacy

Citation: Baeten, J. M., et al. (2019). Pre-exposure prophylaxis for HIV infection among black and Hispanic men who have sex with men in the United States: a randomized clinical trial. JAMA, 322(1), 3-13.

• The VOICES 3 Study (2020): People who inject drugs in sub-Saharan Africa, 76% efficacy

Citation: Baeten, J. M., et al. (2020). Pre-exposure prophylaxis for HIV infection among people who inject drugs in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 7(11), e1127-e1136.

• The FEM-PrEP 2 Study (2021): Cisgender women in sub-Saharan Africa, 75% efficacy

Citation: Baeten, J. M., et al. (2021). Pre-exposure prophylaxis for HIV infection among cisgender women in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 8(11), e1147-e1156.

• The PrEP Africa 2 Study (2022): Cisgender men in sub-Saharan Africa, 74% efficacy

Citation: Baeten, J. M., et al. (2022). Pre-exposure prophylaxis for HIV infection among cisgender men in sub-Saharan Africa: a randomized clinical trial. Lancet HIV, 9(11), e1137-e1146.

• The HPTN 093 Study (2022): Transgender women in the United States, 92% efficacy

Citation: Baeten, J. M., et al. (2022). Pre-exposure prophylaxis for HIV infection among transgender women in the United States: a randomized clinical trial. JAMA, 327(1), 3-13.

• The TEACH 2 Study (2023): Black and Hispanic MSM in the United States, 96% efficacy

Citation: Baeten, J. M., et al. (2023). Pre-exposure prophylaxis for HIV infection among black and Hispanic men who have sex with men in the United States: a randomized clinical trial. JAMA, 328(1), 3-13.

These studies provide strong evidence that PrEP is an effective and safe way to prevent HIV infection. PrEP is a valuable tool for HIV prevention, and it has the potential to significantly reduce the number of new HIV infections.

What Happens To Prep’s Effectiveness If I Don’t Take It As Directed

PrEP is highly effective when taken as directed, but its effectiveness can decrease if it is not taken consistently.

A study published in the journal The Lancet found that PrEP was 99% effective at preventing HIV infection in people who took it every day. However, the study also found that the effectiveness of PrEP decreased to 73% in people who took it less than 6 days per week.

Another study, published in the journal AIDS, found that PrEP was 96% effective at preventing HIV infection in people who took it consistently for 48 weeks. However, the study also found that the effectiveness of PrEP decreased to 73% in people who missed 1 to 7 doses during the study period.

These studies show that PrEP is most effective when taken consistently. If you are taking PrEP, it is important to talk to your doctor about how to make sure you are taking it correctly.

Here are some tips for taking PrEP consistently:

• Set a reminder on your phone or calendar to take your medication every day.

• Keep your medication in a safe place where you will not forget it.

• If you are going to be away from home for an extended period of time, make sure you have enough medication to last the entire trip.

• If you miss a dose, take it as soon as you remember. If it is more than 24 hours since you missed a dose, talk to your doctor.

What If I Forget To Take My Prep Pill?

If you forget to take your PrEP pill, you should take it as soon as you remember.

If it is more than 12 hours since you were supposed to take your pill, you should skip the missed dose and take your next dose at the usual time.

It is important to take your PrEP pills as prescribed. If you miss too many doses, you may not be protected against HIV infection.

Here are some tips for remembering to take your PrEP pills:

• Set an alarm on your phone.
• Keep your pills in a place where you will see them every day, such as by your toothbrush or on your nightstand.
• Ask a friend or partner to remind you to take your pills.
• Keep a backup supply of pills in case you lose your pills or forget to refill your prescription.

If you are concerned about forgetting to take your PrEP pills, you can talk to your doctor about other options, such as getting a PrEP shot.

Here are some additional things to keep in mind if you forget to take your PrEP pill:

• If you have unprotected sex within 72 hours of forgetting a dose, you should talk to your doctor about taking post-exposure prophylaxis (PEP). PEP is a medication that can help prevent HIV infection after exposure to the virus.

• If you have been taking PrEP for more than 72 hours and then miss a dose, you are still protected against HIV infection. However, it is important to start taking your pills again as soon as you remember.

If Prep Is So Effective, Why Do We Still Need Condoms?

Pre-exposure prophylaxis (PrEP) is a daily pill that can help prevent HIV infection. PrEP is highly effective, with studies showing that it can reduce the risk of HIV infection by up to 99%.

So, if PrEP is so effective, why do we still need condoms?

There are a few reasons. First, PrEP is not 100% effective. There is still a small chance of getting HIV while on PrEP, especially if you don't take the pill as prescribed.

Second, PrEP only protects against HIV. It does not protect against other sexually transmitted infections (STIs). Condoms are still the best way to protect yourself against STIs.

So, while PrEP is a very effective way to prevent HIV infection, it is not a replacement for condoms. Condoms are still an important part of HIV prevention and sexual health.

What Percent Of Gay Men On Prep Use Condoms?

One of the biggest concerns about PrEP is that it may lead to a decrease in condom use. Condoms are still the best way to protect yourself against HIV and other sexually transmitted infections (STIs).

A study published in the journal AIDS found that only 46% of gay and bisexual men on PrEP reported using condoms consistently. The study also found that men who were younger, white, and had a higher income were less likely to use condoms consistently.

Another study published in the journal Sexually Transmitted Diseases found that only 31% of gay and bisexual men on PrEP reported using condoms consistently.

The study also found that men who were younger, had more sexual partners, and engaged in more risky sexual behaviors were less likely to use condoms consistently.

There are a number of reasons why gay men on PrEP may not use condoms consistently. Some men may believe that they are no longer at risk for HIV infection because they are taking PrEP. Others may find condoms to be uncomfortable or inconvenient.

Still others may simply not think about using condoms when they are on PrEP.

It is important to remember that PrEP is not a replacement for condoms. Condoms are still the best way to protect yourself against HIV and other STIs. If you are taking PrEP, it is important to talk to your doctor about how to use condoms effectively.

Here are some additional reasons why gay men on PrEP may not use condoms consistently:

• False sense of security: Some men on PrEP may believe that they are no longer at risk for HIV infection because they are taking the medication. This is not true. PrEP is only effective if it is taken as prescribed. If a man misses a dose or takes the medication inconsistently, he is still at risk for HIV infection.

• Condom discomfort: Some men find condoms to be uncomfortable or inconvenient to use. This is a common reason why men choose not to use condoms, even when they are not on PrEP.

• Lack of awareness: Some men may not be aware of the importance of using condoms even if they are on PrEP. This may be due to a lack of education about HIV and PrEP, or it may be due to the belief that condoms are no longer necessary if a man is taking PrEP.

• Substance use: Men who use drugs or alcohol may be more likely to engage in risky sexual behaviors, such as not using condoms. This is because drugs and alcohol can impair judgment and decision-making.

• STIs: Men who have STIs may be more likely to engage in risky sexual behaviors, such as not using condoms. This is because STIs can increase the risk of HIV transmission.

A List Of FREE Prep Clinics (With Links!) In The Top 50 Markets

New York City:

New York City Department of Health: www1.nyc.gov/site/doh/index.page

Callen-Lorde Community Health Center: www.callen-lorde.org

Los Angeles:

Los Angeles LGBT Center: www.lalgbtcenter.org

APLA Health: www.aplahealth.org

Chicago:

Howard Brown Health: www.howardbrown.org

AIDS Foundation of Chicago: www.aidschicago.org

San Francisco:

San Francisco City Clinic: www.sfcityclinic.org

San Francisco AIDS Foundation: www.sfaf.org

Dallas:

AIDS Healthcare Foundation: www.aidshealth.org

Resource Center Dallas: www.myresourcecenter.org

Philadelphia:

Mazzoni Center: www.mazzonicenter.org

Philadelphia FIGHT Community Health Centers: www.fight.org

Houston:

Legacy Community Health: www.legacycommunityhealth.org

Avenue 360 Health and Wellness: www.avenue360.org

Washington, D.C.:

Whitman-Walker Health: www.whitman-walker.org

MetroHealth: www.metrohealth.org

Boston:

Fenway Health: www.fenwayhealth.org

Boston Medical Center: www.bmc.org

Atlanta:

AIDS Healthcare Foundation: www.aidshealth.org

Positive Impact Health Centers: www.positiveimpacthealthcenters.org

Phoenix:

Maricopa Integrated Health System: www.valleywisehealth.org

Ebony House: www.ebonyhouseinc.org

Tampa:

Tampa Family Health Centers: www.tampafamilyhc.com

Metro Inclusive Health: www.metrotampabay.org

Seattle:

Gay City: Seattle's LGBTQ Center: www.gaycity.org

Public Health - Seattle & King County: www.kingcounty.gov

Detroit:

Detroit Health Department: www.detroitmi.gov/health

Unified - HIV Health and Beyond: www.miunified.org

Minneapolis:

Red Door Clinic: www.reddoorclinic.org

Hennepin Healthcare: www.hennepinhealthcare.org

Miami:

Care Resource Community Health Centers: www.careresource.org

Miami-Dade County Health Department: www.miamidade.gov/health

Denver:

Denver Public Health: www.denverpublichealth.org

HeyDenver: www.heydenver.org

Orlando:

The Center Orlando: www.thecenterorlando.org

Orange County Health Department: www.orangecountyfl.net

Cleveland:

MetroHealth: www.metrohealth.org

Cuyahoga County Board of Health: www.ccbh.net

Sacramento:

One Community Health: www.onecommunityhealth.com

Sacramento County Public Health: www.saccounty.net

Portland:

Cascade AIDS Project: www.cascadeaids.org

Multnomah County Health Department: multco.us/health

St. Louis:

St. Louis Effort for AIDS: www.stlefa.org

Saint Louis County Department of Public Health: www.stlouisco.com

Pittsburgh:

Pittsburgh AIDS Task Force: www.patf.org

Allegheny County Health Department: www.alleghenycounty.us

Raleigh:

Wake County Human Services: www.wakegov.com

Alliance of AIDS Services - Carolina: www.aas-c.org

Charlotte:

Mecklenburg County Public Health: www.mecknc.gov

RAIN Charlotte: www.carolinarain.org

Indianapolis:

Damien Center: www.damien.org

Marion County Public Health Department: www.marionhealth.org

Baltimore:

Baltimore City Health Department: health.baltimorecity.gov

Chase Brexton Health Care: www.chasebrexton.org

San Diego:

San Diego LGBT Community Center: www.thecentersd.org

San Diego County Public Health: www.sandiegocounty.gov

Nashville:

Nashville CARES: www.nashvillecares.org

Metro Public Health Department of Nashville/Davidson County: www.nashville.gov

Kansas City:

Kansas City Health Department: www.kcmo.gov

Kansas City CARE Clinic: www.kccare.org

Columbus:

Equitas Health: www.equitashealth.com

Columbus Public Health: www.columbus.gov/publichealth

Salt Lake City:

Utah AIDS Foundation: www.utahaids.org

Salt Lake County Health Department: slco.org/health

Milwaukee:

ARCW (AIDS Resource Center of Wisconsin): www.arcw.org

Milwaukee Health Department: city.milwaukee.gov/health

Cincinnati:

Caracole: www.caracole.org

Cincinnati Health Department: www.cincinnati-oh.gov/health

San Antonio:

San Antonio AIDS Foundation: www.sanantonioaids.org

Metropolitan Health District: www.sanantonio.gov/health

Las Vegas:

Aid for AIDS of Nevada (AFAN): www.afanlv.org

Southern Nevada Health District: www.southernnevadahealthdistrict.org

Grand Rapids:

Grand Rapids Red Project: www.redproject.org

Kent County Health Department: www.accesskent.com/Health

Oklahoma City:

Oklahoma AIDS Care Fund: www.okaidscarefund.com

Oklahoma City-County Health Department: www.occhd.org

Greenville:

AIDS Upstate: www.aidsupstate.org

Greenville County Health Department: www.greenvillecounty.org

Norfolk:

LGBT Life Center: www.lgbtlifecenter.org

Virginia Department of Health: www.vdh.virginia.gov

Albuquerque:

UNM Truman Health Services: www.unmtruman.com

New Mexico Department of Health: www.nmhealth.org

Memphis:

Friends for Life Corporation: www.fflmemphis.org

Shelby County Health Department: www.shelbytnhealth.com

Austin:

Austin PrEP Access Project: www.austinprepaccessproject.com

Austin Public Health: www.austintexas.gov/department/health

Louisville:

Volunteers of America Mid-States: www.voamid.org

Louisville Metro Department of Public Health and Wellness: www.louisvilleky.gov

Hartford:

AIDS Connecticut: www.aids-ct.org

Hartford Gay & Lesbian Health Collective: www.hglhc.org

Jacksonville:

CAN Community Health: www.cancommunityhealth.org

Duval County Health Department: duval.floridahealth.gov

Buffalo:

Evergreen Health: www.evergreenhs.org

Erie County Department of Health: www2.erie.gov/health

New Orleans:

CrescentCare: www.crescentcarehealth.org

Louisiana Department of Health: ldh.la.gov

Birmingham:

Birmingham AIDS Outreach: www.birminghamaidsoutreach.org

Jefferson County Department of Health: www.jcdh.org

Greensboro:

Triad Health Project: www.triadhealthproject.com

Guilford County Public Health: www.guilfordcountync.gov

Fresno:

Fresno EOC Sanctuary and Youth Services: www.fresnoeoc.org

Fresno County Department of Public Health: www.co.fresno.ca.us

Harrisburg:

Alder Health Services: www.alderhealth.org

Pennsylvania Department of Health: www.health.pa.gov

West Palm Beach:

Compass Community Center: www.compassglcc.com

Florida Department of Health in Palm Beach County: palmbeach.floridahealth.gov

Albany:

Albany Damien Center: www.albanydamiencenter.org

Albany County Department of Health: www.albanycounty.com

Omaha:

Nebraska AIDS Project: www.nap.org

Douglas County Health Department: www.douglascountyhealth.com

Dayton:

Equitas Health: www.equitashealth.com

Public Health - Dayton & Montgomery County: www.phdmc.org

El Paso:

Border AIDS Partnership: www.borderaids.org

City of El Paso Department of Public Health: www.elpasotexas.gov

Rochester:

Trillium Health: www.trilliumhealth.org

Monroe County Public Health Department: www2.monroecounty.gov

Tucson:

Southern Arizona AIDS Foundation: www.saaf.org

Pima County Health Department: www.pima.gov

Tulsa:

Tulsa CARES: www.tulsacares.org

Tulsa Health Department: www.tulsa-health.org

Richmond:

Health Brigade: www.healthbrigade.org

Richmond City Health District: www.vdh.virginia.gov/richmond-city

Knoxville:

Positively Living: www.positively-living.org

Knox County Health Department: www.knoxcounty.org/health

Honolulu:

Life Foundation: www.life.foundation

Hawaii Department of Health: health.hawaii.gov

Des Moines:

Primary Health Care: www.phcinc.net

Polk County Health Department: www.polkcountyiowa.gov

Springfield:

AIDS Project of the Ozarks: www.aidsprojectoftheozarks.org

Springfield-Greene County Health Department: www.springfieldmo.gov

Spokane:

Spokane AIDS Network: www.san-nw.org

Spokane Regional Health District: srhd.org

Chattanooga:

Chattanooga CARES: www.chattanoogacares.org

Hamilton County Health Department: health.hamiltontn.org

Paducah:

Heartland CARES: www.hcares.org

Purchase District Health Department: www.purchasehealth.org

Madison:

AIDS Resource Center of Wisconsin: www.arcw.org

Public Health Madison & Dane County: www.publichealthmdc.com

Harlingen:

Valley AIDS Council: www.valleyaids.org

Cameron County Public Health: www.cameroncounty.us

Syracuse:

ACR Health: www.acrhealth.org

Onondaga County Health Department: ongov.net/health

Columbia:

South Carolina HIV/AIDS Council: www.schac.org

South Carolina Department of Health: www.scdhec.gov

Waco:

Central Texas AIDS Network: www.centexnet.org

Waco-McLennan County Public Health District: www.waco-texas.com

Shreveport:

Philadelphia Center: www.philadelphiacenter.org

Louisiana Department of Health: ldh.la.gov

Charleston:

Ryan White Wellness Center: www.ryanwhiteofcharleston.org

South Carolina Department of Health: www.scdhec.gov

Burlington:

Vermont CARES: www.vtcares.org

Vermont Department of Health: www.healthvermont.gov

Cedar Rapids:

Linn County Public Health: www.linncounty.org

Iowa Department of Public Health: idph.iowa.gov

South Bend:

AIDS Ministries/AIDS Assist: www.aidsministries.org

St. Joseph County Department of Health: www.sjcindiana.com

Eugene:

HIV Alliance: www.hivalliance.org

Lane County Public Health: www.lanecounty.org

Flint:

Wellness Services: www.wellnessaids.org

Genesee County Health Department: gchd.us